Research Topic

Treatments

Treatments targeting neurotransmitter imbalances, sleep, and metabolic abnormalities in folate, cobalamin, carnitine, and redox pathways — plus epilepsy, mitochondrial, immune, and microbiome care.

Treatments

Binding Folate Receptor Alpha Autoantibody Is a Biomarker for Leucovorin Treatment Response in Autism Spectrum Disorder

Is a Folate Deficiency Worsening Your Child’s Autism?

Synchrony 2022: Catalyzing Research and Treatments to Benefit Individuals with Neurodevelopmental Disorders including Autism Spectrum Disorders

A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder

The Soluble Folate Receptor in Autism Spectrum Disorder: Relation to Autism Severity and Leucovorin Treatment.

Long COVID Syndrome Presenting as Neuropsychiatric Exacerbations in Autism Spectrum Disorder: Insights for Treatment

Modern Biomarkers for Autism Spectrum Disorder: Future Directions

Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis

A Personalized Multidisciplinary Approach to Evaluating and Treating Autism Spectrum Disorder

Transdermal Electrical Neuromodulation for Anxiety and Sleep Problems in High-Functioning Autism Spectrum Disorder: Feasibility and Preliminary Findings

Ratings of the Effectiveness of Nutraceuticals for Autism Spectrum Disorders: Results of a National Survey

The Effectiveness of Cobalamin (B12) Treatment for Autism Spectrum Disorder: A Systematic Review and Meta-Analysis

A Systematic Review and Meta-Analysis of Immunoglobulin G Abnormalities and the Therapeutic Use of Intravenous Immunoglobulins (IVIG) in Autism Spectrum Disorder

Mitochondrial Fatty Acid β-Oxidation and Resveratrol Effect in Fibroblasts from Patients with Autism Spectrum Disorder

Emerging biomarkers in autism spectrum disorder: a systematic review

Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder

Live interview with Dr. Richard Frye

Treatment of Folate Metabolism Abnormalities in Autism Spectrum Disorder

Mitochondrial Dysfunction in Autism Spectrum Disorder: Unique Abnormalities and Targeted Treatments

Evaluation of the Cunningham Panel™ in pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection (PANDAS) and pediatric acute-onset neuropsychiatric syndrome (PANS): Changes in antineuronal antibody titers parallel changes in patient symptoms

Mitochondrial Dysfunction Is Inducible in Lymphoblastoid Cell Lines From Children With Autism and May Involve the TORC1 Pathway

Nuclear Peroxisome Proliferator-Activated Receptors (PPARs) as Therapeutic Targets of Resveratrol for Autism Spectrum Disorder

Rating of the Effectiveness of 26 Psychiatric and Seizure Medications for Autism Spectrum Disorder: Results of a National Survey

Clinical and Molecular Characteristics of Mitochondrial Dysfunction in Autism Spectrum Disorder

Intravenous immunoglobulin for the treatment of autoimmune encephalopathy in children with autism

Social Skills Deficits in Autism Spectrum Disorder: Potential Biological Origins and Progress in Developing Therapeutic Agents

Comparison of Treatment for Metabolic Disorders Associated with Autism:Reanalysis of Three Clinical Trials

Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial

Patient care standards for primary mitochondrial disease: a consensus statement from the Mitochondrial Medicine Society

Folate metabolism abnormalities in autism: potential biomarkers

The Effect of Mitochondrial Supplements on Mitochondrial Activity in Children with Autism Spectrum Disorder.

Autistic Siblings with Novel Mutations in Two Different Genes: Insight for Genetic Workups of Autistic Siblings and Connection to Mitochondrial Dysfunction.

The Significance of the Enteric Microbiome on the Development of Childhood Disease: A Review of Prebiotic and Probiotic Therapies in Disorders of Childhood.

Primary Mitochondrial Disease and Secondary Mitochondrial Dysfunction: Importance of Distinction for Diagnosis and Treatment

Identification and Treatment of Pathophysiological Comorbidities of Autism Spectrum Disorder to Achieve Optimal Outcomes

Enteric Ecosystem Disruption in Autism Spectrum Disorder: Can the Microbiota and Macrobiota be Restored?

Richard E Frye, MD, PhD. is “All In” for Autistic Children

Treatment for Sleep Problems in Children with Autism and Caregiver Spillover Effects

Approaches to studying and manipulating the enteric microbiome to improve autism symptoms

Treatments for biomedical abnormalities associated with autism spectrum disorder

Clinical potential, safety, and tolerability of arbaclofen in the treatment of autism spectrum disorder

Effectiveness of methylcobalamin and folinic Acid treatment on adaptive behavior in children with autistic disorder is related to glutathione redox status

A review of traditional and novel treatments for seizures in autism spectrum disorder: findings from a systematic review and expert panel

Metabolic effects of sapropterin treatment in autism spectrum disorder: a preliminary study

Redox Metabolism Abnormalities in Autistic Children Associated with Mitochondrial Disease

Cerebral folate receptor autoantibodies in autism spectrum disorder.

Cerebral folate receptor autoantibodies in autism spectrum disorder

Melatonin in autism spectrum disorders: a systematic review and meta-analysis

Traditional and non-traditional treatments for autism spectrum disorder with seizures: an on-line survey

Tetrahydrobiopterin as a novel therapeutic intervention for autism

Electroencephalogram discharges in atypical cognitive development

Propranolol

Folinic Acid (Leucovorin Calcium)

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